Enfermedad Renal Diabética: manejo farmacológico e indicaciones de tratamiento sustitutivo renal

20 de enero de 2021 |
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Enfermedad Renal Diabética: manejo farmacológico e indicaciones de tratamiento sustitutivo renal


Se considera nefropatía diabética a la afectación renal en el enfermo con diabetes mellitus (DM), es decir, la presencia de proteinuria igual o superior a 300 mg/día, en el contexto de DM. Generalmente se acompaña de lesión retiniana y también de hipertensión arterial (HTA), conduciendo en su evolución hacia la aparición de insuficiencia renal crónica (IRC) progresiva.

Esta es una definición clásica, concepto que actualmente se prefiere denominar «Enfermedad Renal Diabética (ERD)».

Sin embargo, en la última década se está describiendo de forma creciente la presencia de daño renal en el enfermo con DM en ausencia de micro albuminuria e, incluso, de proteinuria, por lo que algunos autores preconizan que debemos considerar la existencia de un “fenotipo no proteinúrico” de afectación renal en el paciente con DM.

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